ME, POTS - autoimmune?

Myalgic encephalomyelitis (ME) and  Postural Orthostatic Tachycardia Syndrome (POTS) are co-morbid conditions. Both diseases are suspected to have an autoimmune etiology. Hopefully, future research will clarify both the context and the possible immunological aspects of these diseases. Below is collected references on the subject.

ME og POTS er komorbide tilstande. Begge sygdomme er mistænkt for at have en autoimmun ætiologi. Forhåbentlig vil fremtidig forskning afklare både sammenhængen og de mulige immunologiske aspekter af disse sygdomme. Nedenstående er samlet referencer om emnet.



ME, POTS - co-morbid conditions - autonomic dysfunction



Neurohumoral and haemodynamic profile in postural tachycardia and chronic fatigue syndromes

Impaired cardiac function due to small heart and orthostatic intolerance in patients with myalgic encephalomyelitis

Malfunctioning of the autonomic nervous system in patients with Chronic Fatigue Syndrome: A systematic literature review



ME - immunological dysfunction


Analysis of the Relationship between Immune Dysfunction and Symptom Severity in Patients with ChronicFatigue Syndrome/Myalgic Encephalomyelitis(CFS/ME)

Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and the Potential Role of T Cells

Deficient EBV-Specific B- and T-Cell Response in Patientswith Chronic Fatigue Syndrome

Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Parallels with Autoimmune Disorders

Altered functional B cell subset populations in patients with chronic fatigue syndrome compared to healthy controls

Charakterisierung des phänotypischen und funktionellen Immunstatus bei Patienten mit Chronischem Erschöpfungssyndrom

The Emerging Role of Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome(ME/CFS)

In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation

Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic Encephalomyelitis

Immune Abnormalities in Patients Meeting New Diagnostic Criteria for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Analysis of Neutrophil Function in Severe and Moderately Affected Chronic Fatigue Syndrome Subjects

T Cell Dysregulation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Assessment of Natural Killer Cell Receptors and Activity in Severe and Moderate Chronic Fatigue Syndrome

The role of Dendritic Cells and Monocytes in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics

A narrative review on the similarities and dissimilarities between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and sickness behavior

A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome

Cytotoxic lymphocyte microRNAs as prospective biomarkers for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

The common immunogenic etiology of chronic fatigue syndrome: from infections to vaccines via adjuvants to the ASIA syndrome

Autoantibodies, polymorphisms in the serotonin pathway, and human leukocyte antigen class II alleles in chronic fatigue syndrome: are they associated with age at onset and specific symptoms?

Reduction of [(11)C](+)3-MPB Binding in Brain of Chronic Fatigue Syndrome with Serum Autoantibody against Muscarinic Cholinergic Receptor

Autoantibodies against muscarinic cholinergic receptor in chronic fatigue syndrome

Novel pathomechanisms in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: Do purinergic signalling perturbations and gliosis play a role?



POTS - immunological dysfunction


New evidence of autoimmunity in POTS!

Postural orthostatic tachycardia syndrome: the Mayo clinic experience

Autoimmunoreactive IgGs from patients with postural orthostatic tachycardia syndrome

Autoimmunoreactive IgGs against cardiac lipid raft-associated proteins in patients with postural orthostatic tachycardia syndrome

Autoantibody activation of beta-adrenergic and muscarinic receptors contributes to an "autoimmune" orthostatic hypotension

Agonistic autoantibodies as vasodilators in orthostatic hypotension: a new mechanism

Postural tachycardia syndrome after vaccination with Gardasil

Postural tachycardia syndrome following human papillomavirus vaccination

Postural Orthostatic Tachycardia With Chronic Fatigue After HPV Vaccination as Part of the “Autoimmune/Auto-inflammatory Syndrome Induced by Adjuvants” Case Report and Literature Review

Drug-like actions of autoantibodies against receptors of the autonomous nervous system and their impact on human heart function

Autonomic dysfunction presenting as orthostatic intolerance in patients suffering from mitochondrial cytopathy

Assessment of prevalence and pathological response to orthostatic provocation in patients with multiple sclerosis

Autonomic dysfunction in multiple sclerosis presenting with postural orthostatic tachycardia

Postural orthostatic tachycardia syndrome associated with multiple sclerosis

Autonomic dysfunction presenting as postural orthostatic tachycardia syndrome in patients with multiple sclerosis

Postural orthostatic tachycardia syndrome in a patient with relapsing-remitting optic-spinal multiple sclerosis: A case report and discussion of possible mechanism

Neurally mediated hypotension in systemic lupus erythematosus patients with fibromyalgia

Autonomic nervous symptoms in primary Sjogren's syndrome

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